W.R. Grace, victims don’t settle

A judge had appointed a mediator to try to resolve the dispute between W.R. Grace and victims of asbestos hazards created by that corporation. Today in the news there is a story about the breakdown of that negotiation. Too bad, because this might mean more litigation that W.R. Grace cannot possibly win. Grace tried to pull a stunt last year where they sent letters to victims in Libby Montana essentially saying: you’re not so sick.

Senator Spector calls for asbestos legislation

In February the US Senate considered, and rejected, a bill to create a trust fund and limit mesothelioma lawsuits. Now Pennsylvania Senator Arlen Spector is trying to resurrect the bill to resolve what he calls a “crisis” in an opinion piece in The Hill. Spector wants to prevent mesothelioma victims from suing for full compensation. It is not clear that there is really a crisis here. These large corporations have a lot of money. The victims are individuals, and usually elderly. It’s a question of justice.

The asbestos industry covered up the hazards of the material for decades. Now they should own up to their responsibility.

Woman contracts mesothelioma after exposure to asbestos in husband’s clothing

A woman in York, England got mesothelioma, and the way she was exposed to asbestos was from her husband’s work clothing. “Marjorie Fox, 61, is believed to have contracted fatal cancer after almost 20 years of shaking the dust from her husband Kenneth’s overalls which he wore while working as a carpenter before putting them in the wash.”

We’ve seen this story before, and it is a particularly tragic way in which people get mesothelioma. Workplace hazards affecting not just the workers, but their family members who may never even set foot in the hazardous area.

Australian government also working on asbestos claims

Howard agrees to talks over asbestos. This newspaper article from Australia reports on the prime minister’s willingness to re-engage in talks about an asbestos compensation deal. Like the United States, Australia is trying to cope with the legacy of decades of asbestos use the tragedy of people with mesothelioma. It’s a tough public policy problem, and I don’t envy the legislators who have to grapple with it.

Summary of cutting edge cancer research

The Cheerful Oncologist blog has a post called The Quest, where they compare today’s cancer research to Jason and the Argonauts:

a. commit suicide (by the process known as apoptosis, although a vicious six-foot drop from a wooden scaffold wouldn’t bring any tears to my eyes).

b. wound themselves, if not to the point of apoptosis, at least so severely that signalling compounds (think of blood in the water) are released and attract nearby assassin cells (e.g. dendritic cells – think of sharks closing in) ready to finish the job.

c. fail at angiogenesis, the uncanny ability to influence nearby blood vessels to grow a new supply road into the tumor’s rapidly dividing core, thus ensuring it of a secure source of nutrition and oxygen.

d. become docile, losing the Atilla-the-Hun killer instinct that drives tumors to destroy the only home they have ever known – and unwittingly, themselves along with it.

The blogger concludes: “These are extraordinary times in this quest.”

Interesting times, indeed.

Literature review of pemetrexed

Academics at Texas Tech University did a review of the PubMed/MEDLINE database on pemetrexed (Alimta) articles. They conclude that “Pemetrexed should be used as a standard of care for unresectable MPM [malignant pleural mesothelioma] and recurrent metastatic NSCLC [non-small cell lung cancer].” They also mention decreasing toxicity of the drug by giving the patient steroids and vitamins.